𝔖 Bobbio Scriptorium
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Peptides and monoclonal antibodies which bind to platelet glycoproteins IIb and/or IIIa inhibit clot retraction

✍ Scribed by T. Kent Gartner; Mary L. Ogilvie


Book ID
119037305
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
996 KB
Volume
49
Category
Article
ISSN
0049-3848

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Affinity of fibrinogen binding to platel
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Arg-Gly-Asp (RGD)-containing peptides and the peptide unique to fibrinogen in the C-terminal domain of the gamma chain are important for fibrinogen binding to platelet membrane glycoprotein (GP) II b/III a. We synthesized a unique hybrid peptide of YRGDSPLGGAKQAGDV encompassing the RGD sequence (RGD