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Peptide synthesis containing a B-cell and a T-cell epitope on dextran beads and evaluation of humoral response against bead-peptide construct

✍ Scribed by Luis J. Cruz; Rubén Padrón; Luis J. González; Julio C. Aguilar; Enrique Iglesias; Hilda E. Garay; Viviana Falcón; Eulises Rodríguez; Osvaldo Reyes


Book ID
110298418
Publisher
Springer Netherlands
Year
2000
Tongue
English
Weight
115 KB
Volume
7
Category
Article
ISSN
1573-3149

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## Abstract Polypeptide constructs containing up to four copies of the T cell epitope 306‐318 of influenza virus haemagglutinin have been synthesized on solid phase. Between the copies, a non‐natural PEG‐based spacer amino acid has been introduced. The oligomeric epitopes were analysed by RP‐HPLC a