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Peptide nucleic acid (PNA) binding-mediated gene regulation

✍ Scribed by WANG, Gan; XU, Xiaoxin S

Book ID
110020562
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
228 KB
Volume
14
Category
Article
ISSN
0007-0610

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## Abstract Peptide nucleic acid (PNA) is a nucleobase oligomer in which the entire backbone has been replaced by a backbone composed of __N__‐(2‐aminoethyl)glycine units. In other words, PNA can be regarded as DNA with a neutral peptide backbone instead of a negatively charged sugar–phosphate back