Peptide modification by incorporation of
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Klaus Burger; Norbert Sewald; Christian Schierlinger; Kerstin Mütze; Liza C. Sey
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Article
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1991
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Elsevier Science
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English
⚖ 23 KB
a-Trifluoromethyl a-amino acids are potentially intaresting candidates for modification of biological active peptides. We report on new strategies for asymmetric synthesis of a-trifluoromethyl substituted a-amino acids. Approaches to amino group protection and carboxylic group activation are present