✦ LIBER ✦

Peptide-MHC interaction in autoimmunity

✍ Scribed by Paul J. Fairchild; David C. Wraith

Publisher: Elsevier Science
Year: 1992
Tongue: English
Weight: 862 KB
Volume: 4
Category: Article
ISSN: 0952-7915
DOI: 10.1016/0952-7915(92)90056-k

No coin nor oath required. For personal study only.

✦ Synopsis

Our increased understanding of the molecular basis of autoimmunity owes much to an appreciation of general principles governing peptide-MHC interactions. Such understanding may help resolve long-standing questions concerning autoimmune diseases and aid development of improved therapeutic strategies for their treatment.

📜 SIMILAR VOLUMES

MHC genes in autoimmunity

✍ R.Duncan Campbell; Caroline M. Milner 📂 Article 📅 1993 🏛 Elsevier Science 🌐 English ⚖ 990 KB

MHC heterozygosity and autoimmunity

✍ Masao Kimoto; Hiroyuki Nishimura; Sachiko Hirose; Toshikazu Shirai 📂 Article 📅 1993 🏛 Elsevier Science 🌐 English ⚖ 205 KB

Analysis of MHC-presented peptides: appl

Analysis of MHC-presented peptides: applications in autoimmunity and vaccine development

✍ Roman M. Chicz; Robert G. Urban 📂 Article 📅 1994 🏛 Elsevier Science 🌐 English ⚖ 568 KB

Defining rules for the peptide-MHC class

Defining rules for the peptide-MHC class II interaction

✍ Francesco Sinigaglia; Juergen Hammer 📂 Article 📅 1994 🏛 Elsevier Science 🌐 English ⚖ 615 KB

Non-MHC-linked genes in autoimmune disea

Non-MHC-linked genes in autoimmune diseases

✍ Henri-Jean Garchon 📂 Article 📅 1992 🏛 Elsevier Science 🌐 English ⚖ 886 KB

The gene responsible for the lpr mutation in MRL mice that are prone to systemic lupus erythematosus has been shown to encode the apoptosis-inducing Fas antigen, thus pointing to control of apoptosis as a major regulatory mechanism in autoimmunity. In the non-obese diabetic mouse model for insulin-d

Non-MHC-linked genes in autoimmune disea

Non-MHC-linked genes in autoimmune diseases

✍ Henri-Jean Garchon 📂 Article 📅 1993 🏛 Elsevier Science 🌐 English ⚖ 792 KB