Analysis of MHC-presented peptides: applications in autoimmunity and vaccine development
β Scribed by Roman M. Chicz; Robert G. Urban
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 568 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0167-5699
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Peptide vaccines based on the use of MHC class I restricted epitopes are currently assayed for anti-tumor and anti-viral immunotherapy. With the aim of designing minimally modified, peptidase-resistant analogs, we developed a rational approach based on a detailed understanding of the degradation mec
Analytical biochemistry, in particular the analysis of regulatory proteins that control biological systems and pathways, is dependent on methods of ever-increasing sensitivity. Capillary electrophoresis (CE) has long been recognized as an ultrasensitive analytical technique. In spite of the high sen
## Abstract Analytical biochemistry and synthetic peptide based chemistry have helped to reveal the pivotal role that peptides play in determining the specificity, magnitude and quality of both humoral (antibody) and cellular (cytotoxic and helper T cell) immune responses. In addition, peptide base