Peptide mapping of proteins in cerebrospinal fluid utilizing a rapid preparative two-dimensional electrophoretic procedure and matrix-assisted laser desorption/ionization mass spectrometry
โ Scribed by Pia Davidsson; Carol L. Nilsson
- Book ID
- 117481991
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 274 KB
- Volume
- 1473
- Category
- Article
- ISSN
- 0304-4165
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๐ SIMILAR VOLUMES
Matrix-assisted laser desorption/ionization time-of-flight mass spectra of proteins in cerebrospinal fluid analyzed without prior purification are presented. Less than 100 fmol amounts of proteins in the 10 000 to 20 000 u mass range and linked to human disease (multiple sclerosis, Alzheimer's disea
A novel combination of methods, two-dimensional liquid-phase electrophoresis (2D-LPE) and matrixassisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS), have been used for the analysis of intact brain-specific proteins in cerebrospinal fluid (CSF). 2D-LPE is especially us