𝔖 Bobbio Scriptorium
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Peptide hydroxamic acids inhibit skin collagenase

✍ Scribed by William M. Moore; Curtis A. Spilburg


Book ID
115759762
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
280 KB
Volume
136
Category
Article
ISSN
0006-291X

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The synthesis of peptide hydroxamic acids has been performed on a solid support. A carboxyl group of a peptide synthesized on/xTa-methylbenzhydrylaminΒ’ (pMBHA) resin was converted to a hydroxamate functional group by condensing with NH2OBzl, which was found preferable to NH2OtBu or NH2OTrt. The hydr