Penetration of ciprofloxacin into human lung tissue following intravenous injection

The penetration of ciprofloxacin into br

The penetration of ciprofloxacin into bronchial mucosa, lung parenchyma, and pleural tissue after intravenous administration

✍ M. Dan; K. Torossian; D. Weissberg; R. Kitzes 📂 Article 📅 1993 🏛 Springer 🌐 English ⚖ 231 KB

We have studied the concentrations of ciprofloxacin in serum, bronchial mucosa, lung parenchyma, and pleural tissue after a single intravenous dose of 200 mg in 20 patients subjected to lung surgery. The concentrations of ciprofloxacin in the tissues exceeded that in the serum by 3-fold to 7-fold: s