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Penetration enhancement effect of Pz-peptide, a paracellularly transported peptide, in rabbit intestinal segments and Caco-2 cell monolayers

โœ Scribed by Wan-Ching Yen; Vincent H.L. Lee


Book ID
113275914
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
862 KB
Volume
36
Category
Article
ISSN
0168-3659

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## Abstract Poly[methacrylic acidโ€graftedโ€poly(ethylene glycol)] [P(MAAโ€__g__โ€EG)] is a complexation hydrogel molecularly designed for oral peptide delivery. In this work, the cytotoxicity and insulinโ€transport enhancing effect of P(MAAโ€__g__โ€EG) microparticles on intestinal epithelial cells were e