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Pemphigus serum and captopril induce heat shock protein 70 and inducible nitric oxide synthase overexpression, triggering apoptosis in human keratinocytes

✍ Scribed by A. Baroni; E. Buommino; I. Paoletti; M. Orlando; E. Ruocco; V. Ruocco


Book ID
108667501
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
398 KB
Volume
150
Category
Article
ISSN
0007-0963

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## Abstract Hyperglycemia is the hallmark of diabetes mellitus. Poor glycemic control is correlated with increased cardiovascular morbidity and mortality. High glucose can trigger endothelial cell apoptosis by de‐activation of endothelial nitric oxide synthase (eNOS). eNOS was recently demonstrated