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O2-02 angiotensin II-induced apoptosis of human endothelial cells is inhibited by adiponectin through up-regulation of the association between endothelial nitric oxide synthase and heat shock protein 90

✍ Scribed by Yu-Wei Chin; Lian-Yu Lin; Lin Chien-Yu; Ta-Chen Su; Chiau-Suong Liau

Book ID: 117352551
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 98 KB
Volume: 97
Category: Article
ISSN: 0167-5273
DOI: 10.1016/s0167-5273(04)80081-0

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## Abstract Hyperglycemia is the hallmark of diabetes mellitus. Poor glycemic control is correlated with increased cardiovascular morbidity and mortality. High glucose can trigger endothelial cell apoptosis by de‐activation of endothelial nitric oxide synthase (eNOS). eNOS was recently demonstrated