Pemetrexed disodium in recurrent locally advanced or metastatic squamous cell carcinoma of the head and neck
β Scribed by Pivot, X; Raymond, E; Laguerre, B; Degardin, M; Cals, L; Armand, J P; Lefebvre, J L; Gedouin, D; Ripoche, V; Kayitalire, L
- Book ID
- 111724609
- Publisher
- Nature Publishing Group
- Year
- 2001
- Tongue
- English
- Weight
- 86 KB
- Volume
- 85
- Category
- Article
- ISSN
- 0007-0920
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Forty-two patients with recurrent or metastatic squamous cell carcinoma of the head and neck were treated with vinblastine, bleomycin, and cisplatin. All patients had received prior surgery, radiation or chemotherapy and all had measurable disease. Forty-five percent of the patients responded with a
## Abstract ## Background. Induction chemotherapy may contribute to decreased local and distant recurrences in patients with locally advanced squamous cell carcinoma of the head and neck (SCCHN) resectable for cure. ## Methods. Patients with previously untreated locally advanced stage IIIβIV (N0