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PEG-600: a facile and eco-friendly reaction medium for the synthesis of N-alkyl derivatives of indole-3-carboxyaldehyde

✍ Scribed by Dubey, P.K.; Venkatanarayana, M.

Book ID
120760076
Publisher
Taylor and Francis Group
Year
2010
Tongue
English
Weight
122 KB
Volume
3
Category
Article
ISSN
1751-8253

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PPh3-catalyzed knoevenagel condensation:
PPh3-catalyzed knoevenagel condensation: A facile synthesis of 5-(1H-indol-3-yl)Meth- ylene)-2, 2-Dimethyl-1, 3-Dioxane-4, 6-dione, and their N-alkyl derivatives by using peg-600 as the reaction medium
✍ Muvvala Venkatanarayana; Pramod Kumar Dubey 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 270 KB 👁 1 views

## Abstract Triphenylphosphine (TPP) has been utilized as a novel and efficient catalyst for the Knoevenagel condensation of indole‐3‐carboxaldehydes **1(a–e)**, 1‐methyl‐1H‐indole‐3‐carboxaldehydes **4(a–e)**, and 1‐ethyl‐1H‐indole‐3‐carboxaldehydes **6(a–e)** with the active methylene compound, t