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l -Proline-Catalyzed Knoevenagel Condensation: A Tandem Synthesis of 3-Acetylcoumarinoindoles and Their N -Alkyl Derivatives by Using PEG-600 as the Reaction Medium

✍ Scribed by Venkatanarayana, M.; Dubey, P. K.

Book ID: 121817564
Publisher: Journal of Heterocyclic Chemistry
Year: 2013
Tongue: English
Weight: 299 KB
Volume: 51
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.1784

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## Abstract Triphenylphosphine (TPP) has been utilized as a novel and efficient catalyst for the Knoevenagel condensation of indole‐3‐carboxaldehydes **1(a–e)**, 1‐methyl‐1H‐indole‐3‐carboxaldehydes **4(a–e)**, and 1‐ethyl‐1H‐indole‐3‐carboxaldehydes **6(a–e)** with the active methylene compound, t