Pedigree transmission disequilibrium test for quantitative traits in farm animals
β Scribed by Ding, XiangDong; Wang, ChongLong; Zhang, Qin
- Book ID
- 113083515
- Publisher
- Springer
- Year
- 2012
- Tongue
- English
- Weight
- 607 KB
- Volume
- 57
- Category
- Article
- ISSN
- 1001-6538
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## Abstract Allison ([1997] Am. J. Hum. Genet. 60:676β690) proposed four versions of the transmissionβdisequilibrium test (TDT) for quantitative traits when there is __extremeβthreshold sampling__, i.e., the trios having an offspring trait value between a priori defined thresholds are excluded from
There are numerous statistical methods for quantitative trait linkage analysis in human studies. An ideal such method would have high power to detect genetic loci contributing to the trait, would be robust to non-normality in the phenotype distribution, would be appropriate for general pedigrees, wo