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Pd-Catalyzed Asymmetric Hydrogenation of α-Fluorinated Iminoesters in Fluorinated Alcohol: A New and Catalytic Enantioselective Synthesis of Fluoro α-Amino Acid Derivatives

✍ Scribed by Abe, Hajime; Amii, Hideki; Uneyama, Kenji


Book ID
111691646
Publisher
American Chemical Society
Year
2001
Tongue
English
Weight
46 KB
Volume
3
Category
Article
ISSN
1523-7060

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Powerful probes for revealing the workings of biological systems can be prepared through the judicious replacement of hydrogen atoms with fluorine. [1] The C À F bond has a significant effect on the reactivity, stability, and bioavailability of molecules. [2] Thus, there is a strong demand for a wid