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PCAF acetylates Runx2 and promotes osteoblast differentiation

✍ Scribed by Wang, Chao-Yang; Yang, Shu-Feng; Wang, Zhong; Tan, Jun-Ming; Xing, Shun-Min; Chen, De-Chun; Xu, Sheng-Ming; Yuan, Wen

Book ID
120276356
Publisher
Springer
Year
2013
Tongue
English
Weight
452 KB
Volume
31
Category
Article
ISSN
0914-8779

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## Abstract To investigate the molecular mechanism underlying the differentiation of osteoblasts and chondroblasts, we established a clonal cell lines, RD‐C6, from __Runx2__‐deficient mouse embryos. RD‐C6 cells expressed almost undetectable levels of phenotypes related to osteoblast and chondroblas