Patterns of liver iron accumulation in patients with sickle cell disease and thalassemia with iron overload
β Scribed by Jane S. Hankins; Matthew P. Smeltzer; M. Beth McCarville; Banu Aygun; Claudia M. Hillenbrand; Russell E. Ware; Mihaela Onciu
- Book ID
- 114794774
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 202 KB
- Volume
- 85
- Category
- Article
- ISSN
- 0902-4441
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Patients with sickle cell disease (SCD) appear to be at lower risk of endocrinopathies and cardiac dysfunction than those with thalassemia major (TM). Circulating redox active iron is lower in these patients, possibly due to increased systemic inflammation and circulating cytokines. Hep
## Abstract ## Purpose To evaluate the magnetic properties of the spleen in chronically transfused, ironβoverloaded patients with sickle cell disease (SCD) and thalassemia major (TM) and to compare splenic iron burdens to those in the liver, heart, pancreas, and kidneys. ## Materials and Methods