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Iron chelation therapy for patients with sickle cell disease and iron overload

โœ Scribed by Adlette Inati; Evelyne Khoriaty; Khaled M. Musallam; Ali T. Taher


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
189 KB
Volume
85
Category
Article
ISSN
0361-8609

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## Abstract Patients with sickle cell disease (SCD) appear to be at lower risk of endocrinopathies and cardiac dysfunction than those with thalassemia major (TM). Circulating redox active iron is lower in these patients, possibly due to increased systemic inflammation and circulating cytokines. Hep