Epigenetic silencing of maspin gene expr
β
Frederick E. Domann; Judd C. Rice; Mary J.C. Hendrix; Bernard W. Futscher
π
Article
π
2000
π
John Wiley and Sons
π
French
β 135 KB
π 2 views
Maspin is a tumor suppressor whose expression is lost in many advanced breast cancers. Maspin has been shown to inhibit cell motility, invasion and metastasis; however, its precise role in normal mammary epithelium remains to be elucidated. Although expression of maspin mRNA is low or absent in most