The pattern electroretinogram has assumed greater clinical and experimental significance because of its inner retinal origins. However, clinical tests may be confounded by an artifact. We tested subjects varying reference electrode position and eye stimulated while employing the Dawson-Trick-Litzkow
Pattern electroretinogram: Effects of miosis, accommodation, and defocus
โ Scribed by K. P. Leipert; I. Gottlob
- Publisher
- Springer-Verlag
- Year
- 1987
- Tongue
- English
- Weight
- 542 KB
- Volume
- 67
- Category
- Article
- ISSN
- 0012-4486
No coin nor oath required. For personal study only.
โฆ Synopsis
The effect of miosis, lens accommodation, and defocusing on the various components of the pattern electroretinogram elicited by checkerboard reversal was investigated by employing aperture stops of different size, varying the mean luminance of the target, and inserting spherical lenses of various optical diopters in front of the eye.
After topical administration of pilocarpine (1%) the following changes in the pattern electroretinogram were observed: (i) a decrease of the pupillary diameter leading to a lowered target luminance, which produced attenuation of PERG amplitudes and prolonged latencies, and (ii) defocusing by accommodation of the crystalline lens, which produced attenuation of PERG amplitudes no effect on latencies.
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We studied nine cases of retrobulbar neuritis with confirmed multiple sclerosis and six cases of optic atrophy from other causes. Pattern and focal electroretinograms (macular ERGs) were recorded with high (400 cd/m 2) and low (40 cd/m 2) intensity stimuli. Contrast sensitivity was also measured wit
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