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Patients on injectable diacetylmorphine maintenance have low bone mass

✍ Scribed by KENNETH M. DÜRSTELER-MACFARLAND; ROLAND KOWALEWSKI; NICOLE BLOCH; GERHARD A. WIESBECK; MARIUS E. KRAENZLIN; RUDOLF STOHLER

Book ID
110927702
Publisher
Informa plc
Year
2010
Tongue
English
Weight
129 KB
Volume
30
Category
Article
ISSN
0959-5236

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## Abstract The __Lrp5__ gene is a major determinant of bone mass accrual. It has been demonstrated recently to achieve this function by hampering the synthesis of gut‐derived serotonin, which is a powerful inhibitor of bone formation. In this study we analyzed plasma serotonin levels in patients w