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Patient- and treatment-related factors associated with acute regional toxicity after isolated perfusion for melanoma of the extremities

โœ Scribed by Joost M. Klaase; Bin B.R. Kroon; Bert N. van Geel; Alexander M.M. Eggermont; Hilary R. Franklin; Guus A.M. Hart

Book ID
115695714
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
376 KB
Volume
167
Category
Article
ISSN
0002-9610

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Background. Hyperthermic isolated limb perfusion (HILP) has been shown to be effective for locoregional metastases or local recurrent disease. Locoregional recurrences after previous HILP is an unsolved problem. Methods. HILP with cisplatin, 20-30 mg/l perfused limb volume, was performed in seven p

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## Background: This retrospective study evaluated the benefit of using tumor necrosis factor (tnf) and melphalan administered via an isolated limb perfusion (ilp) in a series of patients with metastatic melanoma who failed initial ilp with chemotherapeutics. ## Methods: Seventeen patients with ex