## Abstract Alginate, a natural polysaccharide, has been widely used in tissue engineering and drug delivery, butlike other biomaterials, it causes inflammation by unknown mechanisms. We hypothesized that alginate would stimulate innate immune responses through macrophage receptors. In this study,
Pathways of macrophage activation and innate immunity
โ Scribed by Gregory J. Bancroft; John P. Kelly; Paul M. Kaye; Vincent McDonald; Caroline E. Cross
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 399 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0165-2478
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Innate recognition of infection in vertebrates can lead to the induction of adaptive immune responses through activation of dendritic cells (DCs). DCs are activated directly by conserved pathogen molecules and indirectly by inflammatory mediators produced by other cell types that recognise such mole
## Abstract Many of the healthcare consequences of cigarette smoking could be due to its ability to compromise the immune system, and in respiratory diseases like chronic obstructive pulmonary disease (COPD), a constant low level of infection could be responsible for some of the symptoms/pathology.