Pathways involved inDrosophilaand human cancer development: the Notch, Hedgehog, Wingless, Runt, and Trithorax pathway

Somatic mutations in the notch, NF-KB, P

Somatic mutations in the notch, NF-KB, PIK3CA, and hedgehog pathways in human breast cancers

✍ Xiang Jiao; Laura D. Wood; Monica Lindman; Sian Jones; Phillip Buckhaults; Korne 📂 Article 📅 2012 🏛 John Wiley and Sons 🌐 English ⚖ 967 KB

## Abstract Exome sequencing of human breast cancers has revealed a substantial number of candidate cancer genes with recurring but infrequent somatic mutations. To determine more accurately their mutation prevalence, we performed a mutation analysis of 36 novel candidate cancer genes in 96 human b