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Pathways for repairing and tolerating the spectrum of oxidative DNA lesions

✍ Scribed by Brian R. Berquist; David M. Wilson III

Book ID
119211677
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
672 KB
Volume
327
Category
Article
ISSN
0304-3835

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Complexities of the DNA base excision re
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✍ Sankar Mitra; Istvan Boldogh; Tadahide Izumi; Tapas K. Hazra πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 204 KB πŸ‘ 2 views

## Abstract Oxidative damage represents the most significant insult to organisms because of continuous production of the reactive oxygen species (ROS) in vivo. Oxidative damage in DNA, a critical target of ROS, is repaired primarily via the base excision repair (BER) pathway which appears to be the