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DNA repair is responsible for the presence of oxidatively damaged DNA lesions in urine

✍ Scribed by Marcus S. Cooke; Mark D. Evans; Rosamund Dove; Rafal Rozalski; Daniel Gackowski; Agnieszka Siomek; Joseph Lunec; Ryszard Olinski


Book ID
113808593
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
181 KB
Volume
574
Category
Article
ISSN
0027-5107

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## Abstract Oxidative damage represents the most significant insult to organisms because of continuous production of the reactive oxygen species (ROS) in vivo. Oxidative damage in DNA, a critical target of ROS, is repaired primarily via the base excision repair (BER) pathway which appears to be the