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Pathophysiological mechanisms of genetic absence epilepsy in the rat

✍ Scribed by L Danober; C Deransart; A Depaulis; M Vergnes; C Marescaux

Book ID
117457789
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
918 KB
Volume
55
Category
Article
ISSN
0301-0082

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Involvement of nitric oxide (NO) in the regulation of the epileptic activity was studied in WAG/Rij rats, a genetic model of absence epilepsy. I.c.v. administration of NO donors: S-nitroso-Nacetylpenicillamine (SNAP, 0.5 and 5 pg), 3-morpholino-sydnonimine (SIN-1, 0.5 and 5 pg) or sodium nitroprussi