## Abstract In order to investigate a possible correlation beween __in vitro__ transformation and tumorigenicity __in ovo__, a new temperature‐sensitive class T mutant of Rous Sarcoma Virus was isolated with a lower (39·5C) restrictive temperature for morphological transformation. This lower restri
✦ LIBER ✦
Pathogenicity of the Chicken Sarcoma Virus (Schmidt–Ruppin) for Amphibians and Reptiles
✍ Scribed by SVET-MOLDAVSKY, GEORGE J.; TRUBCHENINOVA, LIDIA; RAVKINA, LUCY I.
- Book ID
- 109656536
- Publisher
- Nature Publishing Group
- Year
- 1967
- Tongue
- English
- Weight
- 803 KB
- Volume
- 214
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/214300a0
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## Abstract A cytopathic effect was induced by the Schmidt‐Ruppin strain of Rous sarcoma virus (RSV‐SR) in five of nine rat tumor cell lines tested in vitro. The cells showed irreversible cytopathic change as early as 24‐48 h after infection. Of the leukemogenic and tumorigenic viral agents tested,