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Pathogenesis of polycythemia vera—new concepts

✍ Scribed by David W. Golde; Martin J. Cline

Publisher
John Wiley and Sons
Year
1976
Tongue
English
Weight
326 KB
Volume
1
Category
Article
ISSN
0361-8609

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✦ Synopsis

Abstract

Data presently available suggest that polycythemia vera is an acquired clonal disorder of the pluripotent stem cell resulting in expansion of committed stem cell pools, most prominently in the erythroid line. In vitro and in vivo studies suggest that erythropoiesis in polycythemia vera is at least partially modulated by erythropoietin.

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