Treatment of polycythemia vera with hydroxyurea
β Scribed by Rivka Sharon; Ilana Tatarsky; Yehudith Ben-Arieh
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 270 KB
- Volume
- 57
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
6-thioguanine, an antimetabolite not potentiated by allopurinol, has been used in the treatment of 29 patients with polycythemia Vera. All but two of the patients had been treated previously by venesection and/or radioactive phosphorus (32p) and/or alkylating agents. The usual dose was 40-160 mg dai
In polycythemia Vera (PV), treatment with chlorambucil and radioactive phosphorus (p32) increases the risk of leukemic transformation from 1% to 13-14%. This risk has been estimated to be 1-5.9% with hydroxyurea (HU) therapy. When compared with historical controls, the risk with use of HU does not a