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Pathogenesis of Experimental Ebola Zaire Virus Infection in BALB/c Mice

✍ Scribed by T.R. Gibb; M. Bray; T.W. Geisbert; K.E. Steele; W.M. Kell; K.J. Davis; N.K. Jaax


Book ID
114475744
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
782 KB
Volume
125
Category
Article
ISSN
0021-9975

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Six rhesus and two vervet monkeys were infected intraperitoneally with Ebola virus. They developed an acute haemorrhagic fever with skin rash 4 days later and died 6--12 days after infection. Histopathological lesions of acute necrosis were present in the liver, spleen, lymph nodes, lungs and testes