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The pathology of experimental Ebola virus infection in monkeys

✍ Scribed by A. Baskerville; E. T. W. Bowen; G. S. Platt; L. B. McArdell; D. I. H. Simpson

Publisher: John Wiley and Sons
Year: 1978
Tongue: English
Weight: 743 KB
Volume: 125
Category: Article
ISSN: 0022-3417
DOI: 10.1002/path.1711250303

No coin nor oath required. For personal study only.

✦ Synopsis

Six rhesus and two vervet monkeys were infected intraperitoneally with Ebola virus. They developed an acute haemorrhagic fever with skin rash 4 days later and died 6--12 days after infection. Histopathological lesions of acute necrosis were present in the liver, spleen, lymph nodes, lungs and testes. The presence of fibrin thrombi in several organs was suggestive of the occurrence of disseminated intravascular coagulation during the infection.

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