## Abstract Twentyβnine histologically verified cases of Paget's disease of the breast treated at the Hadassah University Hospital in the years 1949β1972 were followed up and analyzed. Dividing this material into two groups according to the presence or absence of a palpable breast tumor revealed si
Pathogenesis and treatment of paget's disease of the BREAST
β Scribed by Joseph F. Paone; R. Robinson Baker
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- English
- Weight
- 544 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0008-543X
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## Abstract ## Background and Objectives Paget disease of the breast has long been recognized as a distinct clinical disease. The clinical manifestations and outcomes of Paget disease of the breast were reviewed to understand its earlier diagnostic clues and achieve an optimal treatment plan. ##
The goals of treatment of Paget's disease must be readdressed in the context of the availability of potent bsphosphonate compounds, including pamidronate and, more recently, alendronate and risedronate. These agents differ from the traditional mainstays of therapy, salmon calcitonin and etidmnate, i