Paget's disease of the breast
β Scribed by H. Freund; M. Maydovnik; N. Laufer; A. L. Durst
- Publisher
- John Wiley and Sons
- Year
- 1977
- Tongue
- English
- Weight
- 354 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0022-4790
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
Twentyβnine histologically verified cases of Paget's disease of the breast treated at the Hadassah University Hospital in the years 1949β1972 were followed up and analyzed. Dividing this material into two groups according to the presence or absence of a palpable breast tumor revealed significant difference in behavior and survival. Patients with a breast mass (34%) had a 50% axillary lymph node involvement and behaved as with any other ordinary breast cancer, with a 5βyear survival rate of 40% and a 10βyear survival rate of 33%. Patients with no palpable breast mass (66%) had only a 10.5% lymph node involvement, the 5βyear survival rate being 94% and the 10βyear survival rate being 91%. Delay in diagnosis seems to play no significant factor in survival rates and outcome. We believe radical mastectomy to be the treatment of choice in all cases of Paget's disease of the breast.
π SIMILAR VOLUMES
A 67-year-old woman developed a cutaneous horn on the nipple of her right breast. Biopsy of the skin underlying the horn disclosed Paget's disease of the breast. An intraductal adenocarcinoma of the same breast was found on mastectomy. High index of suspicion is mandatory in evaluating all nipple le
## RESULTS. The median follow-up for surviving patients was 62 months. Three pa- ## Michigan. tients (10%) developed a recurrence in the breast as the only site of first failure,