Paternity in patients with testicular germ cell cancer: Pretreatment and post-treatment findings
β Scribed by Vejby Hansen, Peter; Glavind, Karin; Panduro, Jytte; Pedersen, Mogens
- Book ID
- 123146952
- Publisher
- Elsevier Science
- Year
- 1991
- Weight
- 720 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0277-5379
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With the use of cisplatin-based combination chemotherapy, metastatic testicular germ-cell tumors can be cured in 70% to 80% of patients. The combination of cisplatin, etoposide and bleomycine (PEB) is considered standard therapy.
Sperm counts, serum gonadotropins, and androgen levels were investigated in 39 seminoma patients and 58 patients with a nonseminomatous germ cell tumor of the testis after unilateral orchiectomy. In 58% of the patients, the total sperm count was below the lower reference value (80 million). A multir