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Paternal origin of the de novo constitutional t(11;22)(q23;q11)

✍ Scribed by Ohye, Tamae; Inagaki, Hidehito; Kogo, Hiroshi; Tsutsumi, Makiko; Kato, Takema; Tong, Maoqing; Macville, Merryn V E; Medne, Livija; Zackai, Elaine H; Emanuel, Beverly S

Book ID
109849307
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
360 KB
Volume
18
Category
Article
ISSN
1018-4813

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High incidence of familial breast cancer
High incidence of familial breast cancer segregates with constitutional t(11;22)(q23;q11)
✍ Ilse Wieland; Petra Muschke; Marianne Volleth; Albrecht RΓΆpke; Antje-Friederike πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 266 KB

## Abstract In a family with a high incidence of postmenopausal breast cancer and a case of glioblastoma, the constitutional translocation t(11;22)(q23;q11.2) was shown to segregate with the malignancies. The breakpoints in this family coincided with the common breakpoints in t(11;22) as shown by a