Patent ductus arteriosus in premature infants: A review of current management
โ Scribed by William A. Neal; Martha D. Mullett
- Publisher
- Springer
- Year
- 1982
- Tongue
- English
- Weight
- 469 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0172-0643
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Sixteen premature infants were treated with indomethacin, either orally or intravenously, in order to close a symptomatic patent ductus arteriosus requiring mechanical ventilation. Positive effect was obtained in 4 of the 10 orally treated patients and in 1 of the 6 with intravenous administration.
Central blood flow (CBF) was estimated by an intravenous 133-xenon technique in six preterm infants before and after administration of indomethacin for closure of patent ductus arteriosus. CBF fell in all infants (range 12%-40%), the mean fall was 24% (P less than 0.005). Though none of the infants