Passive transfer of experimental myasthenia gravis via antigenic modulation of acetylcholine receptor
β Scribed by Heleni Loutrari; Anna Kokla; Socrates J. Tzartos
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 427 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0014-2980
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Myasthenia gravis (MG) is a neuromuscular disorder of man caused by a humoral response to the acetylcholine receptor (AChR). Most of the antibodies in MG and in experimental autoimmune myasthenia gravis (EAMG) are directed to the extracellular portion of the AChR alpha subunit, and within it, primar
## Antigen-specific therapy of experimental myasthenia gravis with acetylcholine receptor-gelonin conjugates in viva* Rats suffering from experimental autoimmune myasthenia gravis (EAMG) induced by previous immunization with foreign acetylcholine receptor (AChR) were treated with AChR-toxin conjug
## Abstract Aspects of acetylcholine receptor immunology and circulating receptor antibodies are reviewed with regard to both human and experimental myasthenia gravis. Receptor antibodies that have negligible crossβreactivity with skeletal muscle receptor can nonetheless cause destruction of the po