Participation of three lymphoid cell types in the in vitro activation of cell-mediated immunity to a syngeneic gross virus-induced lymphoma in rats
โ Scribed by J.Y. Djeu; M. Glaser; K.Y. Huang; R.B. Herberman
- Book ID
- 115810954
- Publisher
- Elsevier Science
- Year
- 1976
- Tongue
- English
- Weight
- 752 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0008-8749
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## Abstract Conditions are described for optimal stimulation in vitro of lymphocytes from rats primed in vivo with syngeneic MuLVโG leukaemia cells. Cultures generate effector cells which show high cytotoxic activity against leukaemic cells. Specific stimulation can be obtained with leukaemic cells
## Abstract The internal viral protein, p30^1^, has been identified by cytotoxicity tests using xenogeneic sera, on MuLVโGโinduced rat lymphoma cells. In this system internal virion antigens, and in particular p30, are cytotoxic target antigens for syngeneic antibody and cellโmediated cytotoxicity;