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Participation of three lymphoid cell types in the in vitro activation of cell-mediated immunity to a syngeneic gross virus-induced lymphoma in rats

โœ Scribed by J.Y. Djeu; M. Glaser; K.Y. Huang; R.B. Herberman


Book ID
115810954
Publisher
Elsevier Science
Year
1976
Tongue
English
Weight
752 KB
Volume
23
Category
Article
ISSN
0008-8749

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๐Ÿ“œ SIMILAR VOLUMES


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## Abstract Conditions are described for optimal stimulation in vitro of lymphocytes from rats primed in vivo with syngeneic MuLVโ€G leukaemia cells. Cultures generate effector cells which show high cytotoxic activity against leukaemic cells. Specific stimulation can be obtained with leukaemic cells

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## Abstract The internal viral protein, p30^1^, has been identified by cytotoxicity tests using xenogeneic sera, on MuLVโ€Gโ€induced rat lymphoma cells. In this system internal virion antigens, and in particular p30, are cytotoxic target antigens for syngeneic antibody and cellโ€mediated cytotoxicity;