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Partial Inactivation of Translation Termination Factors Causes Suppression of Frameshift Mutations in the Yeast Saccharomyces cerevisiae

✍ Scribed by V. N. Kulikov; O. N. Tikhodeev; F. S. Forafonov; A. S. Borkhsenius; V. V. Alenin; S. G. Inge-Vechtomov

Book ID: 110350249
Publisher: SP MAIK Nauka/Interperiodica
Year: 2001
Tongue: English
Weight: 67 KB
Volume: 37
Category: Article
ISSN: 1022-7954
DOI: 10.1023/a:1016606412918

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Earlier genetic analyses have identified a mitochondrial +1 frameshift suppressor (MF1) in the 15S rRNA region of a leaky mitochondrial frameshift mutant and the respective wild-type strain 777-3A (Weiss-Brummer et al. 1987). Further genetic analyses revealed that for the observed spontaneous frames