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At least two nuclear-encoded factors are involved together with a mitochondrial factor (MR1) in spontaneous mitochondrial frameshift-suppression of the yeastS. cerevisiae

✍ Scribed by Brigitte Weiss-Brummer; Hajime Sakai; Monika Magerl-Brenner


Publisher
Springer-Verlag
Year
1987
Tongue
English
Weight
349 KB
Volume
12
Category
Article
ISSN
0172-8083

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✦ Synopsis


Earlier genetic analyses have identified a mitochondrial +1 frameshift suppressor (MF1) in the 15S rRNA region of a leaky mitochondrial frameshift mutant and the respective wild-type strain 777-3A (Weiss-Brummer et al. 1987). Further genetic analyses revealed that for the observed spontaneous frameshift suppression in M5631 the mitochondrial factor (MF1) must act together with at least two dominant nuclearencoded factors.