[Part 2: Biological Sciences] || Relationship between X-Ray Exposure and Malignant Transformation in C3H 10T1/2 Cells
β Scribed by Ann R. Kennedy, Maurice Fox, Gary Murphy and John B. Little
- Book ID
- 123674432
- Publisher
- National Academy of Sciences
- Year
- 1980
- Tongue
- English
- Weight
- 734 KB
- Volume
- 77
- Category
- Article
- ISSN
- 0027-8424
- DOI
- 10.2307/9743
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## Abstract We have compared the interferon sensitivity of parental 10T1/2 cells, having a phenotype characteristic of normal cells, with that of transformed cells isolated after Xβirradiation or treatment with methylcholanthrene. Transformed cells were 10β to 20βfold less sensitive than the parent
## Abstract Fibrin clot retraction (FCR) was studied in C3H/10T1/ 2 murine fibroblasts. These cells were able to induce FCR with high efficiency during resting phase as well as during active growth. C3H/10/T1/2 cells which became tumorigenic after Xβirradiation lacked FCR activity. Nonβtumorigenic