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[Part 1: Biological Sciences] || Activation and Fusion Induced by 1α ,25-dihydroxyvitamin D3and Their Relation in Alveolar Macrophages

✍ Scribed by Etsuko Abe, Yoshiko Shina, Chisato Miyaura, Hirofumi Tanaka, Takamune Hayashi, Shiro Kanegasaki, Motoo Saito, Yasuho Nishii, Hector F. DeLuca and Tatsuo Suda


Book ID
123631621
Publisher
National Academy of Sciences
Year
1984
Tongue
English
Weight
956 KB
Volume
81
Category
Article
ISSN
0027-8424

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We have reported that the active form of vitamin D3, 1 alpha,25-dihydroxyvitamin D3 [1 alpha,25(OH)2D3], directly induces activation and fusion of mouse alveolar macrophages (Abe et al., 1983, 1984). The activated state appeared to be a prerequisite to the fusion of macrophages. Macrophages began to

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We have reported that the active form of vitamin D3, 1 alpha, 25-dihydroxy-vitamin D3 [1 alpha, 25(OH)2D3], directly induces the fusion of mouse alveolar macrophages (Abe et al: Proc. Natl. Acad. Sci. USA 80:5583-5587, 1983). The fusion process can be divided into two phases: the 1 alpha,25(OH)2D3-d