1α,25-Dihydroxyvitamin D3 directly induces fusion of alveolar macrophages by a mechanism involving RNA and protein synthesis, but not DNA synthesis

Fusion of mouse alveolar macrophages ind

Fusion of mouse alveolar macrophages induced by 1α,25-dihydroxyvitamin D3 involves extracellular, but not intracellular, calcium

✍ Cheng He Jin; Chisato Miyaura; Hirofumi Tanaka; Jiro Takito; Etsuko Abe; Tatsuo 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 571 KB

We have reported that the active form of vitamin D3, 1 alpha, 25-dihydroxy-vitamin D3 [1 alpha, 25(OH)2D3], directly induces the fusion of mouse alveolar macrophages (Abe et al: Proc. Natl. Acad. Sci. USA 80:5583-5587, 1983). The fusion process can be divided into two phases: the 1 alpha,25(OH)2D3-d