𝔖 Bobbio Scriptorium
✦   LIBER   ✦

PARP inhibition in BRCA-mutated breast and ovarian cancers

✍ Scribed by Stephen L Chan; Tony Mok


Book ID
117307041
Publisher
The Lancet
Year
2010
Tongue
English
Weight
336 KB
Volume
376
Category
Article
ISSN
0140-6736

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


BRCA2 mutations in primary breast and ov
✍ Lancaster, Johnathan M.; Wooster, Richard; Mangion, Jonathon; Phelan, Catherine πŸ“‚ Article πŸ“… 1996 πŸ› Nature Publishing Group 🌐 English βš– 378 KB
BRCA1 and BRCA2 mutations in breast/ovar
✍ L. Stuppia; P. Di Fulvio; G. Aceto; S. Pintor; S. Veschi; V. Gatta; A. Colosimo; πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 112 KB πŸ‘ 2 views

We report on the screening of the entire BRCA1/BRCA2 coding sequence by SSCP, PTT, and direct sequencing in 68 Italian families with recurrent breast or ovarian cancer. For each investigated proband, the probability of being carrier of a BRCA1/BRCA2 mutation was evaluated using the BRCAPRO software.

BRCA1 mutation analysis in 83 Spanish br
✍ Orland DΓ­ez; Joan CortΓ©s; Montserrat DomΓ¨nech; Joan Brunet; Elisabeth Del RΓ­o; C πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 French βš– 142 KB πŸ‘ 2 views

A group of 83 Spanish BC/OC families were analysed for BRCA1 germ-line mutations. Analysis of the entire coding sequence was carried out by SSCP and PTT. We identified 5 frameshift mutations: 185delAG (2 times), 189insTGTC, 1241delAC, and 5537delA and 3 missense mutations in BRCA1: 330A G G, 1240C G

BRCA1-related breast cancer in Austrian
✍ Teresa M. U. Wagner; Regine A. MΓΆslinger; Daniela Muhr; Gudrun Langbauer; Kora H πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 French βš– 76 KB πŸ‘ 2 views

We identified 17 BRCA1 mutations in 86 Austrian breast and ovarian cancer families (20%) that were screened for mutations by denaturing high-performance liquid chromatography (DHPLC) and the protein truncation test (PTT). Eleven distinct mutations were detected, 4 of them (962del4, 2795del4, 3135del

Prevalence of BRCA1 and BRCA2 mutations
✍ Muhammad U. Rashid; Anbreen Zaidi; Diana Torres; Faisal Sultan; Axel Benner; Bil πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 French βš– 312 KB πŸ‘ 2 views

## Abstract Among Asian countries, Pakistan has the highest rates of breast and ovarian cancer. To assess the contribution of the __BRCA1__ and __BRCA2__ germ line mutations to these high rates, we conducted the first study of 176 Pakistani breast and ovarian cancer patients, selected on family his