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Parkinson's disease with involvement of the parasympathetic ganglia

✍ Scribed by S. Takeda; K. Yamazaki; T. Miyakawa; H. Arai


Book ID
104744221
Publisher
Springer-Verlag
Year
1993
Tongue
English
Weight
488 KB
Volume
86
Category
Article
ISSN
0001-6322

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✦ Synopsis


We report the distribution of Lewy bodies in an 83-year-old man who was diagnosed histopathologically as having Parkinson's disease. Many sections were taken from the brain, spinal cord, spinal dorsal root ganglia and peripheral autonomic systems. In the central nervous system, Lewy bodies were present in many of the areas already reported by previous authors. In the peripheral nervous system, Lewy bodies were present in the sympathetic ganglia, enteric nervous system of the alimentary tract and the submandibular ganglion, which is a peripheral parasympathetic ganglion. The present case indicates that the peripheral parasympathetic ganglia are involved in the disease process of Parkinson's disease.


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Lewy bodies in the lower sacral parasymp
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Lewy bodies were observed incidentally in the neurons of the dorsal group of nucleus intermediolateralis of the 3rd sacral segment of the spinal cord in a 74-year-old male with Parkinson's disease. The findings indicate the degeneration of the preganglionic parasympathetic neurons innervating the in