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Lewy bodies in the lower sacral parasympathetic neurons of a patient with Parkinson's disease

✍ Scribed by K. Oyanagi; K. Wakabayashi; E. Ohama; S. Takeda; Y. Horikawa; T. Morita; F. Ikuta


Publisher
Springer-Verlag
Year
1990
Tongue
English
Weight
573 KB
Volume
80
Category
Article
ISSN
0001-6322

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✦ Synopsis


Lewy bodies were observed incidentally in the neurons of the dorsal group of nucleus intermediolateralis of the 3rd sacral segment of the spinal cord in a 74-year-old male with Parkinson's disease. The findings indicate the degeneration of the preganglionic parasympathetic neurons innervating the internal anal sphincter. The correlation between the findings and the mechanism of constipation in this disease are discussed.


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Parkinson's disease: an immunohistochemi
✍ K. Wakabayashi; H. Takahashi; E. Ohama; F. Ikuta πŸ“‚ Article πŸ“… 1990 πŸ› Springer-Verlag 🌐 English βš– 882 KB

We performed immunohistochemical analysis of specimens from three autopsied patients with Parkinson's disease, using antibodies to tyrosine hydroxylase (TH), vasoactive intestinal polypeptide (VIP), somatostatin, met-enkephalin, leu-enkephalin and substance P in an attempt to reveal the types of neu