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Parkinson's disease dementia: at the crossroads of α-synuclein, tau and amyloid-β

✍ Scribed by Irwin, David; Lee, V.; Trojanowski, J.


Book ID
122134151
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
49 KB
Volume
35
Category
Article
ISSN
0197-4580

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## Abstract Although alpha‐synuclein is the main constituent of Lewy bodies, cerebrospinal fluid determination on its own does not seem fundamental for the diagnosis of synucleinopathies. We evaluated whether the combination of classical biomarkers, Aβ~1–42~, total tau, phosphorylated tau, and α‐sy